POPEK, TOMASZ,PATEL, KISHORE,ALAKHOV, VALERY,PIETRZYNSKI, GRZEGORZ
申请号：
CA2753641
公开号：
CA2753641C
申请日:
2010.02.24
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention is directed to pharmaceutical compositions comprising:(a) bendamustine, (b) a chargedcyclopolysaccharide, and (c) a stabilizing agent having a charge opposite tothat of the cyclopolysaccharide. Such composition providesunexpectedly desirable stability in reactive environments such as plasma,coupled with unexpectedly desirable anticancer activity.Such compositions are suitable for injection or infusion into patients in needfor treatment with bendamustine.
