ALAKHOV, VALERY,PIETRZYNSKI, GRZEGORZ,PATEL, KISHORE,POPEK, TOMASZ
申请号:
CA2805805
公开号:
CA2805805C
申请日:
2011.02.23
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention is directed to pharmaceutical compositions including: (a) bendamustine, (b) a first charged cyclopolysaccharide, and (c) a stabilizing agent which is a second charged cyclopolysaccharide having a charge opposite to that of the first charged cyclopolysaccharide. The composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. The compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.