A tryptanthrin compound for use in therapy as an adjuvant to provide an enhanced immune response to an antigen, wherein tryptanthrin compound having Formula (I): wherein A, B, C, D, E, F , G, and H are independently selected from carbon and nitrogen, or A and B and / or C and D can be taken together to be nitrogen or sulfur R1, R2, R3, R4, R8, and R10 are independently selected from the group consisting of hydrogen, halogen, lower alkyl, alkyl, substituted alkyl, cycloalkyl, heterocyclyl, alkylheterocyclyl, substituted heterocyclyl, substituted alkenyl, amino, (substituted ) (alkyl) amino, imino, lower haloalkyl, hydroxy, alkoxy, substituted alkoxy, hydroxyalkylthio, nitro, alkylsulfonyl, N-alkylsulfonamide, arylalkyl, arylalkylaryl, arylalkyl, aryloxy, arylamino, acylamino, aciloxiamino, alkylaminoacylamino, alkylaminosulfonylamino, alkylamino, alkenylamino, dialkylamino, alkoxyalkylamino, alcoxialquilheterociclilo, mercaptoalcoxialquilo, cyano, formyl, -COOR11 wherein R11 is hydrogen, loweralkyl, aryl, heterocyclyl, monosaccharide or disaccharide, and -CONR12R13 wherein R12 and R13 are independently selected from hydrogen, lower alkyl , aryl, heterocyclyl, saccharide, peptide and amino acid residues or R2 and R3 taken together form an aromatic six-membered ring R7 and R9 are independently selected from hydrogen, halogen, lower alkyl, lower haloalkyl, cycloalkyl, heterocyclyl, substituted heterocyclyl or heterocyclylalkyl and R1, R2, R3, R4, R7, R8, R9, and R10 are absent when the ring atom to which would otherwise be attached is sulfur or nitrogen double bond or a pharmaceutically acceptable salt, provided that R1, R2, R3, R4, R7, R8, R9, and R10 are not all hydrogen when A, B, C, D, E, F, and H are carbon.Un compuesto de triptantrina para uso en terapia en forma de un adyuvante para proporcionar una respuesta inmune potenciada a un antígeno, en el que compuesto de triptantrina tiene la Fórmula (I): en la que A, B, C, D, E, F, G, y H se seleccionan independienteme
