Ihab S. Darwish,Jiaxin Yu,Hui Hong,Rajinder Singh,Sambaiah Thota,Xiang Xu
申请号:
US13348384
公开号:
US20120108606A1
申请日:
2012.01.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structurein which R1, R2, R4, D, E, J, T, p, q and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.