Hui Hong,Xiang Xu,Jiaxin Yu,Rajinder Singh,Ihab S. Darwish,Sambaiah Thota
申请号:
US12272581
公开号:
US08119809B2
申请日:
2008.11.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structurein which R1, R2, R4, E, T, n and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.