대전대학교 산학협력단;LEE, HAE GYUN;DAEJEON UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION;이해균
发明人:
LEE, HAE GYUN,이해균,SONG, GYU YONG,송규용,KIM, DONG HEE,김동희,CHOI, HAK JOO,최학주
申请号：
KR1020120012076
公开号：
KR1020130090941A
申请日:
2012.02.07
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition containing an extract of ISRK crude drug complex for preventing and treating diabetes and diabetes complication is provided to obtain a pharmaceutical composition and a health food for preventing and treating diabetes and diabetes complication without insulin resistance. CONSTITUTION: A pharmaceutical composition for preventing and treating diabetes and diabetes complication contains 0.001-50 wt% of an extract of crude drug complex as an active ingredient. The crude drug complex includes Helianthus tuberosus, Circium japonicum, malt, Lithospermum erythrorhizon, bamboo leaves, Cortex mori radicis, Grifola umbellate, Poria cocos, corn silk, Citrus unshiu peels, Hovenia dulcis THUNB, Hovenia dulcis, Lycium chinense, Ulmus macrocarpa, jujube, Longanae Arillus, Astragalus membranaceus BUNGE, Atractylodes japonica, Cornus fruit, Glycyrrhizae radix, Angelica gigas, Paeoniae Radix, Rehmanniae radix Cnidii rhizoma, Eucommia ulmoides, and Acanthopanacis cortex. The extract is prepared using a polar solvent selected among water, C1-C4 alcohols, and a mixture thereof. [Reference numerals] (AA) 18th August； (BB) 25th August； (CC) 1st September； (DD) 8th September； (EE) 15th September； (FF) 22th September； (GG) 29th September본 발명은 ISRK 복합생약 추출물을 포함하는 당뇨병 및 당뇨합병증 예방 및 치료를 위한 조성물에 관한 것으로서, 본 발명의 ISRK 복합생약 추출물은 혈중 포도당 농도의 급격한 상승을 억제 및 조절하고 혈중 인슐린 분비를 증진시키며, 혈당, 중성지방, 저밀도 콜레스테롤 수준을 감소시켜 혈당증(fasting hyperglycemia)을 완화시키는 혈당강하 효능과 인슐린에 대한 저항성을 감소시킴으로서 당뇨병 및 당뇨합병증 예방 및 치료를 위한 약학조성물 및 건강기능식품에 유용하게 이용될 수 있다.
