Triazolyl pyrimidinone compounds as PDE2 inhibitors

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Shen, Dong-Ming,Sinz, Christopher, J.,Crespo, Alejandro,Wilson, Jonathan, E.,McCracken, Troy,Xu, Shimin,Li, Haitang

申请号：

AU2016233618

公开号：

AU2016233618A1

申请日:

2016.03.11

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention is directed to pyrimidine carboxamide compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinsons disease, Parkinsons disease dementia (PDD), or Huntingtons disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

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中国工程科技知识中心

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