SHEN DONG MING,SINZ CHRISTOPHER J,CRESPO ALEJANDRO,WILSON JONATHAN E,MCCRACKEN TROY,XU SHIMIN,LI HAITANG
申请号:
IN201747030427
公开号:
IN201747030427A
申请日:
2017.08.28
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention is directed to pyrimidine carboxamide compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders such as schizophrenia psychosis Parkinson s disease Parkinson s disease dementia (PDD) or Huntington s disease and those associated with striatal hypofunction or basal ganglia dysfunction.