MORRIELLO, Gregori J.,CHANG, Lehua,FORSTER, Ashley,CHEN, Yili,DWYER, Michael, P.,BERGER, Richard,WANG, Ming,NANDA, Kausik K.,BUNDA, Jaime L.,SHIPE, William D.
申请号:
EP16815100
公开号:
EP3313852A4
申请日:
2016.06.20
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention is directed to pyrimidine carboxamide compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.