KC Sunil Kumar,KC Sunil Kumar,WALLACE David Mark,WALLACE David Mark,HOOD John,HOOD John,BARROGA Charlene F.,BARROGA Charlene F.
申请号：
SI201131411
公开号：
SI2605652T1
申请日:
2011.08.17
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
The present invention discloses ²-diketones, ³-diketones or ³-hydroxyketones or analogs thereof, that activate Wnt/²-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinsons disease, strokes, ischemic cerebral disease, epilepsy, Alzheimers disease, depression, bipolar disorder, schizophrenia eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.
