KC, Sunil Kumar,Wallace, David Mark,Hood, John,Barroga, Charlene F.
申请号：
AU2018200333
公开号：
AU2018200333A1
申请日:
2018.01.15
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018200333A120180201.pdf#####ABSTRACT [0279] The present invention discloses p-diketones, y-diketones or yhydroxyketones or analogs thereof, that activate Wnt/p-catenin signalling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy； osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia； eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.
