Provided is a pharmaceutical composition for oral administration enabling size reduction and improved solubility, elutability, and oral absorbability of (2R)-N-({5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2H-benzimidazole-2-ylidene)-3-oxopropanoyl]-2-fluorophenyl} sulfonyl)-2-hydroxypropane imide-amide (hereafter, compound A) or a pharmaceutically acceptable salt thereof. The pharmaceutical composition for oral administration contains a polymer or amorphous form of compound A or a pharmaceutically acceptable salt thereof.本發明係提供一種(2R)-N-({5-〔3-(2,5-二全氟苯基)-2-(1,3-二氫-2H-苯並咪唑-2-亞基)-3-氧基丙醯基〕-2-全氟苯基}磺醯基)-2-羥丙基亞胺醯胺(以下稱作化合物A)或其製藥學上許可的鹽,實現改善溶解性、改善溶出性、改善經口吸收性以及緻密化之經口投予用醫藥組成物。前述經口投予用醫藥組成物,係含有化合物A或其製藥學上許可的鹽之非晶質體以及高分子。
