Food composition against obesity or pharmaceutical composition against obesity containing 4-methylsulfinyl-3-butenyl isothiocyantate, precursor and derivatives of 4-methylsulfinyl-3-butenyl isothiocyantate
The present invention contains 4-methylsulfinyl-3-butenyl isothiocyantate or 4-methylsulfonyl-3-butenyl isothiocyanate precursor or derivative as an active ingredient. The present invention relates to a food composition for preventing obesity and a pharmaceutical composition for treating obesity, the method comprising: inhibiting fat accumulation and inhibiting expression of PPARγ, an important transcription factor expressed upon differentiation into adipocytes, 4-methylsulfonyl By containing 3-butenyl isothiocyanate as an active ingredient, an excellent obesity prevention or treatment effect is exhibited.본 발명은 4-메틸설포닐-3-부테닐 이소티오시아네이트(4-methylsulfinyl-3-butenyl isothiocyantate) 또는 4-메틸설포닐-3-부테닐 이소티오시아네이트 전구체 또는 유도체를 유효성분으로 함유하는 것을 특징으로 하는 비만 예방용 식품 조성물 및 비만 치료용 약학 조성물에 관한 것으로, 지방 축적 억제 효과, 지방 세포로의 분화시 발현되는 중요한 전사인자인 PPARγ의 발현 저해 효과를 발휘하는 4-메틸설포닐-3-부테닐 이소티오시아네이트를 유효성분으로 함유함으로써 우수한 비만 예방 또는 치료효과를 발휘한다.
