Disclosed is a composition having a nitric oxide production inhibitory activity with little cytotoxicity. The dried fish meat of the same fish or the processed product of the dried fish meat as an active ingredient is characterized in that the dried fish and the dried fish have the same habit. [Selection figure] None【課題】細胞毒性がほとんどない一酸化窒素産生阻害活性を備える組成物を提供すること。【解決手段】ドジョウおよびドジョウと棲息態様が同じ魚類の乾燥魚肉または前記乾燥魚肉の処理物を有効成分として含むことを特徴とする。【選択図】なし