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METHOD OF PRODUCING OF PHARMACOLOGICALLY ACTIVE LIPOSOMAL COMPOSITION CONTAINING CYTOCHROME C, AND LIPOSOMAL COMPOSITION OBTAINED BY THIS METHOD
专利权人:
TOVARISTVO Z OBMEZHENOU VIDPOVIDALNISTU "NANOMEDTRAST"
发明人:
GRYGOR'IEVA Ganna S.,KATSAI Oleksii H.,KRASNOPOLSKYI Yurii M.,PROKHOROV Vitalii V.,KHROMOV Oleksandr S.,PASYECHNIKOVA Nataliya V.,DOBRELIA Natalia V.
申请号:
US201715793184
公开号:
US2018116957(A1)
申请日:
2017.10.25
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
This invention relates to pharmaceutics and a method of producing of liposomal composition containing cytochrome c and the pharmacologically active liposomal composition obtained by this method, which can be used as a means of polyfunctional pharmacotherapy, especially for ophthalmology, hematology and cardiology.;A method of producing of liposomal composition containing cytochrome c, the method includes preparing mixture of solutions of lipids in an organic solvents, drying in vacuum the mixture and emulsifying it in aqueous medium containing cytochrome c, adding of cryoprotectant, homogenization of the emulsion, filtration and freeze-drying, and according to the invention the lipids are egg or soybean phosphatidylcholine with one or two of lipids from the group consisting of dipalmitoylphosphatidylglycerol, dipalmitoylphosphatidylcholine, distearoylphosphatidylcholine, diphosphatidylglycerol, phosphatidylglycerol, phosphatidylinositol or dioleoyloxypropy trimethylammonium, whereas the ratio of phosphatidylc
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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