MITCHELL, TRACY S.,GOSSELIN, MICHAEL L.,LIPOVSEK, DASA,PARKER, REX,CAMPHAUSEN, RAY,DAVIS, JONATHAN,FABRIZIO, DAVID
申请号:
CA2943241
公开号:
CA2943241A1
申请日:
2015.03.19
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.