KIM, DAE JIN,金大振,KIM, JUNG KUK,金正国,金正國,JUNG, SUNG YOUB,郑圣烨,鄭聖燁,KWON, SE CHANG,权世昌,權世昌
申请号:
TW107126155
公开号:
TW201920664A
申请日:
2018.07.27
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
Provided is a conjugate in which an immunoglobulin Fc region is linked to an iduronate-2-sulfatase enzyme through a non-peptide polymer linker moiety. Further, provided are a conjugate, a method for preparing the same, and a composition including the same in which a non-peptide polymer linker moiety is specifically linked to an immunoglobulin Fc.本案提供一種接合物,其中免疫球蛋白Fc區通過非肽聚合物鏈接基部分與艾杜醣醛酸鹽-2-硫酸酯酶鏈接。此外,本案提供接合物、該接合物之製備方法,以及包含該接合物的組成物,其中非肽聚合物鏈接基部分與免疫球蛋白Fc特異性鏈接。