PROCÉDÉ DE DÉTECTION SIMULTANÉE DE SIGNAUX DE FLUORESCENCE ET RAMAN POUR PLUSIEURS CIBLES DE SIGNAL DE FLUORESCENCE ET RAMAN, ET APPAREIL D'IMAGERIE MÉDICALE POUR LA DÉTECTION SIMULTANÉE DE PLUSIEURS CIBLES EN UTILISANT LE PROCÉDÉ
JEONG, DAE HONG,KANG, KEON WOOK,LEE, DONG SOO,LEE, YOON SIK,KIM, GUN SUNG,JUN, BONG HYUN,PAENG, JIN CHUL,LEE, HO YOUNG,LEE, YUN SANG
申请号:
EP11816631
公开号:
EP2604168A4
申请日:
2011.08.11
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and to a medical imaging device for simultaneously detecting multiple targets using the method. The method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets according to one embodiment of the present invention comprises the following steps: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. According to the present invention, the simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. In addition, according to the present invention, as an examination may be performed by injecting surface-enhanced Raman marker particles, into which fluorescent components are introduced, into the body of the animal using a spray or the like, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.