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ORAL RAPAMYCIN PREPARATION AND USE FOR STOMATITIS
专利权人:
Rapamycin Holdings; Inc.
发明人:
VAUGHN, Dana, M.
申请号:
EP15779860
公开号:
EP3131546A4
申请日:
2015.04.16
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The disclosure teaches counter-intuitive methods for treating stomatitis using oral mTOR inhibiting preparations such as preparations of microcapsules and nanoparticles including an inhibitor of the mammalian target of rapamycin. The methods, preparations and other teachings are useful in various respects, especially for assisting in the treatment, prevention and management of stomatitis in feline subjects and, most especially, the treatment and management of Feline Chronic Gingivo-Stomatitis (FOGS), with secondary applications also related to management of gingivitis and autoimmune mucosal disorders. Disclosed embodiments illustrate multi-week dosing regimens and also address needs for alternative preparations or manufacturing processes that ensure efficacy while improving other performance characteristics such as storage stability, biodistribution, dosage cost, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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