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DMBQ Composition for Improving Protecting or Treating Sarcopenia comprising DMBQ as Active Ingredient
专利权人:
KOREA FOOD RESEARCH INSTITUTE
发明人:
HA, TAE YOUL,하태열,JANG, YOUNG JIN,장영진,AHN, JI YUN,안지윤,HUR, JIN YOUNG,허진영,JUNG, CHANG HWA,정창화,SON, HYO JEONG,손효정,CHOI, WON HEE,최원희,HA, TAE YOULKR,JANG, YOUNG JINKR,AHN, JI YUNKR,HUR, JIN YOUNGKR,JUNG, CHANG HWAKR,SON, HYO JEONGKR,CHOI, WON HEEKR
申请号:
KR1020160134525
公开号:
KR1017716800000B1
申请日:
2016.10.17
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention provides a composition for alleviating, preventing, or treating sarcopenia and obesity. The effective component of the present invention, 2,6-dimethoxy-1,4-benzoquinone (DMBQ) is a substance originated from grains that can be easily sourced, and has an economical advantage. The DMBQ increases the expression of genes related to muscle hypertrophy by activating downstream Akt/mTOR/pS6K signalling pathway of IGF-1, which is an important regulator in increasing skeletal muscles; increases the size and strength of muscles by reducing the expression of genes related to atrophy; and reduces fat tissues.본 발명은 근감소증 및 비만의 개선, 예방 또는 치료용 조성물을 제공한다. 본 발명의 유효성분인 DMBQ(2,6-다이메톡시-1,4-벤조퀴논)은 곡류 유래 물질로 원료 수급이 용이하고, 경제적인 이점을 갖는다. 상기 DMBQ는 골격근 증가의 중요 조절자인 IGF-1의 하위 Akt/mTOR/pS6K 신호전달을 활성화시켜 근육 비대 관련 유전자의 발현을 증가시키고, 근감소 관련 유전자의 발현을 감소시켜 근육의 크기 및 근력을 증가시키고, 지방조직을 감소시킨다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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