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Devices, systems, and methods for excavating cancer cells
专利权人:
Georgia Tech Research Corporation
发明人:
Bellamkonda, Ravi V.,Jain, Anjana
申请号:
AU2011285639
公开号:
AU2011285639A1
申请日:
2011.08.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Methods, devices, and systems are provided for guiding tumor movement, particularly in vivo for treatment of patients. The method may include implanting into a tissue site where tumor cells are present a device having one or more surface structures or substrates, such as aligned nanofibers, which provide physical guidance cues for directing the migration of the tumor cells from the first tissue location to a selected second location, for tumor cell extraction or death. The devices and systems may include a cytotoxic agent for contacting tumor cells migrated via the substrate. All or a portion of the at least one substrate may include one or more biochemical cues, such as a coating of laminin or another protein, which may be provided in a concentration gradient to facilitate uni -directional tumor cell migration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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