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Sequence of nucleotides and peptides GSE 24.2 of dyskerin, which can induce telomerase activity, method for obtaining same, therapeutic compositions and applications thereof
专利权人:
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSIDAD AUTONOMA DE MADRID—FUNDACION GENERAL;UNIVERSIDAD POLITECNICA DE VALENCIA
发明人:
Rosario Perona Abellon,Rosario Machado Pinilla,Leandro Sastre Garzon,Isabel Sanchez Perez,Jose Ramon Murguia Ibanez
申请号:
US14740890
公开号:
US09587002B2
申请日:
2015.06.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to a compound that induces or activates telomerase activity based on the nucleotide sequence of the GSE 24.2 fragment of dyskerin or the protein or peptide sequence encoded by said nucleotide sequence. Another part of the invention relates to vectors that comprise said sequence and cells transformed thereby, and pharmaceutical compositions that contain all these elements. These compositions may be used in the treatment of diseases from the following group: ageing or acceleration of ageing, neurodegenerative diseases and dyskeratosis congenita.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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