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CRYSTALLINE 1-(3-FLUOROPHENYL)-5-METHYL-2-(1H)PYRIDONE, THE PREPARATION METHODS, COMPOSITIONS AND APPLICATIONS THEREOF
专利权人:
发明人:
申请号:
EP09719945.9
公开号:
EP2251328B1
申请日:
2009.03.10
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Crystalline pyridone compound, which is the white needle crystal containing no water and other crystallization solvents. Its unit cell belongs to monoclinic system and has space group of P21/n, wherein a = 3.8512(2), b= 20.2535(12), c = 12.1628(6) Å, β = 92.850(5)° and crystal cell volume V = 947.53(9) Å3. Pyridone compound crystal of this form has the needed properties for preparing or making treatment compositions in large scale. It can be used for treating organs fibrosis of liver, kidney, lung and etc. and reducing skin scars.
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