Crystalline 1-(3-fluorophenyl)-5-methyl-2-(1H)pyridone, the preparation methods, compositions and applications thereof

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专利权人:

Jiamei Chen

发明人:

Jiamei Chen,Tongbu Lu,Song Chen,Jinghui Cai,Zhaolin Fu,Zhe He,Xuefeng Wang,Chaozhi Wang,Yonge Liu,Lijian Tao,Gaoyun Hu

申请号：

US12920320

公开号：

US08232408B2

申请日:

2009.03.10

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Crystalline pyridone compound, which is the white needle crystal containing no water and other crystallization solvents. Its unit cell belongs to monoclinic system and has space group of P21/n, wherein a=3.8512(2), b=20.2535(12), c=12.1628(6) Å, β=92.850(5)° and crystal cell volume V=947.53(9) Å3. Pyridone compound crystal of this form has the needed properties for preparing or making treatment compositions in large scale. It can be used for treating organs fibrosis of liver, kidney, lung and etc. and reducing skin scars.

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