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FORMULAÇÃO LÍQUIDA CONTENDO ANTICORPO DE ELEVADA CONCENTRAÇÃO
专利权人:
F. HOFFMANN-LA ROCHE AG;CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
TOSHIYUKI MORICHIKA,DAISUKE KAMEOKA,YOSHIMI IMAEDA,TERUTOSHI MAEDA,OLIVER BORIS STAUCH
申请号:
PT08866971
公开号:
PT2238985E
申请日:
2008.12.26
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.
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