CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN - LA ROCHE AG
发明人:
Toshiyuki MORICHIKA,Daisuke KAMEOKA,Yoshimi IMAEDA,Terutoshi MAEDA,Oliver Boris STAUCH
申请号:
US16390197
公开号:
US20200079857A1
申请日:
2019.04.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.