CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG
发明人:
MORICHIKA, TOSHIYUKI,KAMEOKA, DAISUKE,IMAEDA, YOSHIMI,MAEDA, TERUTOSHI,STAUCH, OLIVER BORIS
申请号:
HRP20120903
公开号:
HRP20120903T1
申请日:
2012.11.09
申请国别(地区):
HR
年份:
2012
代理人:
摘要:
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.