A suturing device for apposition of tissues is disclosed. The device comprisesan introducer having a first port, a second port, and a suture port formed therethrough.First and second needle assemblies are disposed through the first and secondports, respectively. First and second ferrules are removably disposed in thefirst and second ports, respectively, at a distal end of the introducer. The firstand second ferrules are configured to receive the first and second assemblies,respectively, for tissue apposition. A fastener for attaching suture wiresis disposed in the suture port at the distal end of the introducer. First and secondsuture wires are attached to the first and second ferrules, respectively, andextend through the fastener for apposition of tissues.
