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NOVEL BICYCLIC COMPOUND OR SALT THEREOF
专利权人:
发明人:
KITADE MAKOTO,YAMASHITA SATOSHI,OHKUBO SHUICHI
申请号:
IN6028/DELNP/2013
公开号:
IN2013DN06028A
申请日:
2013.07.05
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Provided is a novel bicyclic compound which is capable of inhibiting HSP90 and has a carcinostatic effect. A compound represented by general formula (I) or a salt thereof. In general formula (I): at least one of X1, X2, X3 and X4 represents N or N-oxide and the remainders are the same or different and represent C-R2 one or two of Y1, Y2, Y3 and Y4 represent C-R4 and the remainders are the same or different and represent CH or N R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1-4 hetero atoms, said hetero atoms being selected from among N, S and O R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. R3 represents -CO-R5, etc. R4 represents a hydrogen atom, -N(R7)(R8), etc. R5 represents a hydroxyl group, an amino group, etc. and R7 and R8 are the same or different and represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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