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Phenylimidazole compounds
专利权人:
Tadao Shibutani;Satoshi Kido;Koushi Iwata
发明人:
Tadao Shibutani,Koushi Iwata,Satoshi Kido
申请号:
US13145041
公开号:
US08329739B2
申请日:
2010.02.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
[Object] To provide a pharmaceutical product (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, etc.[Solving Means] A phenylimidazole compound represented by the following General Formula (1):wherein, R1 represents a hydrogen atom, a phenyl lower alkyl group optionally having a substituent, or a pyridyl lower alkyl group optionally having a substituent, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted lower alkyl groups. One of R2 and R3 represents a hydrogen atom and the other represents a lower alkoxy group. R4 represents a phenyl group optionally having a substituent. R5 and R6 are the same or different, and represent a hydrogen atom or a lower alkyl group. R7 and R8 are the same or different, and represent a hydrogen atom or a lower alkoxy group. However, when R1 represents an unsubstituted phenyl lower alkyl group, R2 represents a lower alkoxy group, R3 represents a hydrogen atom, R4 represents a phenyl group optionally having a substituent, and R5 represents a hydrogen atom, R6 is not a hydrogen atom.
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