MACDONALD, GREGOR JAMES,BARTOLOME-NEBREDA, JOSE MANUEL
申请号:
HRP20120913
公开号:
HRP20120913T1
申请日:
2012.11.13
申请国别(地区):
HR
年份:
2012
代理人:
摘要:
The present invention relates to (1-benzyl-piperidin-4-yl)-(4-alkoxy-pyridazin-3-y1)-amines that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.