Macdonald, Gregor James,Bartolome-Nebreda, Jose Manuel,Van Gool, Michiel Luc Maria
申请号：
AU2008240729
公开号：
AU2008240729B2
申请日:
2008.04.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to [1- (benzyl) -piperidin-4-yl] -( [1, 3,4] thiadiazol-2-yl)- amine and [1- (benzyl) -piperidin-4-yl] - (thiazol-2-yl) -amine derivativesof formula (I) that are fast dissociating dopamine 2 receptor antagonists, processesfor preparing these compounds, pharmaceutical compositions comprising thesecompounds as an active ingredient. The compounds find utility as medicines fortreating or preventing central nervous system disorders, for example schizophrenia,by exerting an antipsychotic effect without motor side effects.
