PROCÉDÉ D'ESTIMATION DE DÉBITS, DE GRADIENTS DE PRESSION, DE RÉSERVE D'ÉCOULEMENT CORONAIRE ET DE RÉSERVE D'ÉCOULEMENT FRACTIONNAIRE À PARTIR DE DONNÉES DE DISTRIBUTION DE CONTRASTE BASÉE SUR UN ANGIOGRAMME DE TOMOGRAPHIE ASSISTÉE PAR ORDINATEUR SPÉCIFIQUES AU PATIENT
SEO, JUNG HEE;THE JOHNS HOPKINS UNIVERSITY;MITTAL, RAJAT;LARDO, ALBERT C.
发明人:
MITTAL, RAJAT,LARDO, ALBERT, C.,SEO, JUNG HEE
申请号：
EP13840252
公开号：
EP2900142A4
申请日:
2013.04.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
An embodiment in accordance with the present invention provides a method for non-invasively determining the functional severity of coronary artery stenosis. The method includes gathering patient-specific data related to concentration of a contrast agent within a coronary artery of a patient using a coronary computed tomography angiography scan (CCTA). The patient-specific data is used to calculate a patient-specific transluminal attenuation gradient for the coronary artery of the patient. The patient specific transluminal attenuation gradient is used to determine an estimate of a coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and/or fractional flow reserve for the patient. Coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and fractional flow reserve can then be used to estimate the functional severity of coronary artery stenosis.
