Christopher J. Bungard;James J. Perkins;Jesse J. Manikowski;Robert Meissner
发明人:
Christopher J. Bungard,Jesse J. Manikowski,James J. Perkins,Robert Meissner
申请号:
US12445901
公开号:
US08119681B2
申请日:
2007.10.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives of formula I (I) as glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.