CHRISTOPHER J. BUNGARD,JESSE J. MANIKOWSKI,JAMES J. PERKINS,ROBERT MEISSNER
申请号:
BRPI0718505
公开号:
BRPI0718505A2
申请日:
2007.10.23
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
The present invention is directed to 2-[1-phenyl-5-hydroxy or methoxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives of formula I (I) as glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.