Disclosed are novel preparations of Actinidia, and particularly species of hardy kiwifruit, as well as compositions comprising the same. Also disclosed is the use of these preparations of Actinidia to prevent and/or treat a variety of diseases in which regulation of the immune response is effective, including both allergic and non-allergic inflammatory disease, viral infection, and cancer. Methods related to making and using these compositions are also described.La présente invention concerne des préparations à base dActinidia, et plus particulièrement despèces rustiques de kiwi, ainsi que des compositions en comprenant. Linvention concerne également lutilisation des ces préparations pour prévenir et/ou traiter diverses affections concernées par la régulation des réponses immunitaires (affections allergiques et non allergiques, infections virales, cancers). Linvention concerne aussi des procédés de fabrication et dutilisation de ces compositions.