Modified HSV gD protein and vaccine containing same

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专利权人:

KM Biologics Co.; Ltd.

发明人:

MORI, Hiroaki,NISHIMURA, Tomohiro,SHIMIZU, Hiroyuki,KOUBE, Akihiro,KATAYAMA, Takahiro

申请号：

AU2018323502

公开号：

AU2018323502A2

申请日:

2018.08.29

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

This modified HSV gD protein is a modified protein of a herpes simplex virus (HSV) envelope glycoprotein D (gD) wherein the modified HSV gD protein is modified so that at least one of the B cell epitopes (decotopes) having low or no neutralizing antibody-inducing activity does not function as an epitope as compared to B cell epitopes present in the receptor-binding domain (RBD) in the ectodomain of wild type HSV gD.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/