HUMAN MONOCLONAL ANTIBODIES AGAINST THE MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS (MERS-COV) AND ENGINEERED BISPECIFIC FUSIONS WITH INHIBITORY PEPTIDES
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV;THE UNIVERSITY OF HONG KONG
发明人:
Dimiter S. Dimitrov,Tianlei Ying,Tina W. Ju,Kwok Yung Yuen
申请号：
US15030165
公开号：
US20160264647A1
申请日:
2014.10.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides polypeptides (e.g., antibodies) and fusion proteins that target a epitope in the receptor binding domain (RBD) of the spike (S) glycoprotein of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The polypeptides and fusion proteins can be used to treat and prevent MERS-CoV infection in mammals.
