CONTINUOUSLY EXPRESSED THERAPEUTIC RNAS FOR TARGETED PROTEIN BINDING AND METHODS FOR THEIR USE

• 收藏
• 分享

专利权人:

发明人:

Ka Ming PANG,John J. ROSSI

申请号：

US15800836

公开号：

US20180125878A1

申请日:

2017.11.01

申请国别(地区):

US

年份:

2018

代理人:

摘要：

An RNA composition comprising an RNA aptamer and an shRNA molecule and/or an miRNA molecule are provided. The RNA composition may include an aptamer component that binds an enzymatic protein within a target cell and an shRNA and/or an miRNA component that facilitates trafficking of the aptamer within the target cell, such as, trafficking from the nucleus into the cytoplasm. The RNA aptamer and the shRNA and/or the miRNA component of the composition can be a fusion or independent molecules.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/