ANTICORPS MONOCLONAL ANTI-FACTEUR DE NÉCROSE TUMORALE ALPHA HUMAIN ET SON UTILISATION

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专利权人:

DANYANG ZHENGYUAN BIOTECH CO. LTD.

发明人:

LIU, QINGFA

申请号：

EP09841729

公开号：

EP2409992A4

申请日:

2009.03.20

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

A protein capable of specifically binding to human TNF± (tumor necrosis factor alpha) is provided, i.e. human anti-TNF± monoclonal antibody derived from human B cells. The light and heavy chains of the antibody comprise the amino acid sequences as shown in SEQ ID NO: 8 and SEQ ID NO: 9 or 10, respectively. The encoding gene, the Fab antibody and the use in the preparation of the medicament for treating TNF±-related inflammation of the anti-TNF± antibody are also provided.

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