Tim Hugo Maria Jonckers,Pierre Jean-Marie Bernard Raboisson,Koen Vandyck,Steven Maurice Paula Van Hoof,Lili Hu,Abdellah Tahri
申请号：
US13836465
公开号：
US08933052B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Compounds of the formula I:including any possible stereoisomers thereof, wherein: R4 is a monophosphate, diphosphate or triphosphate ester or R4 isR7 is optionally substituted phenyl, optionally substituted naphthyl, or optionally substituted indolyl R8 and R8′ are hydrogen, C1-C6alkyl, benzyl, or phenyl or R8 and R8′ form C3-C7cycloalkyl R9 is C1-C10alkyl, C3-C7cycloalkyl, phenyl or phenyl-C1-C6alkyl, wherein the phenyl moiety in phenyl or phenyl-C1-C6alkyl is optionally substitutedor a pharmaceutically acceptable salt or solvate thereofpharmaceutical formulations and the use of compounds I as HCV inhibitors.
