PROBLEM TO BE SOLVED: To provide a flavonoid glycoside ester sufficiently having water solubility, while having antimicrobial activity, and to provide an antimicrobial agent, anti-inflammatory agent, and antioxidant containing the same.SOLUTION: The invention provides a flavonoid glycoside ester obtained by the esterification of one or more hydroxyl groups that the carbons of an α-glucosyl, β-glucosyl, and α-rhamnosyl group have, to an α-glucosyl naringin, α-glucosylrutin, or α-glucosyl hesperidin, using carboxylic acid or an ester thereof, under the presence of an esterifiable enzyme and an antimicrobial agent, anti-inflammatory agent, and antioxidant containing the flavonoid glycoside ester as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT