The University Court of The University of Aberdeen
发明人:
Barelle, Caroline,Muller, Mischa,Calabro, Valerie,Bikker, Jack A.,Steven, John,Tchistiakova, Lioudmila,Kovalenko, Oleg,Olland, Andrea
申请号:
AU2018201899
公开号:
AU2018201899A1
申请日:
2018.03.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018201899A120180412.pdf#####ABSTRACT The present invention provides a single domain specific binding molecule having the structure5 FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have aminol 0 acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.