The University Court of The University of Aberdeen
发明人:
Barelle, Caroline,Muller, Mischa,Calabro, Valerie,Bikker, Jack A.,Steven, John,Tchistiakova, Lioudmila,Kovalenko, Oleg,Olland, Andrea
申请号:
AU2020202026
公开号:
AU2020202026A1
申请日:
2020.03.20
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020202026A120200409.pdf#####ABSTRACT The present invention provides a single domain specific binding molecule having the structure 5 FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.