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PREPARATION EN POUDRE DESTINEE A ETRE ADMINISTREE PAR VOIE NASALE
专利权人:
LTD.;ASKA PHARMACEUTICAL CO.
发明人:
MINATO, KOICHI,FUJISAWA, TOMOYA,SHIMIZU, KENJI,SAITO, TAKAHISA,YAJIMA, HIROYA,SASAKI, KAZUHIRO
申请号:
CA3083757
公开号:
CA3083757A1
申请日:
2018.11.22
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The purpose of the present invention is to prepare a powder preparation for nasal administration that includes, as an active ingredient, a particulate steroid hormone having an average particle size of 50300µm. The powder preparation for nasal administration may further include a water-soluble polymer (in particular, a water-soluble polysaccharide such as cellulose comprising a hydroxyalkyl group). The particulate steroid hormone may be formed from testosterone and/or a derivative thereof. The water-soluble polymer may be particulate. The proportion of the water-soluble polymer may be around 150 parts by weight with respect to 1 part by weight of the particulate steroid hormone. This powder preparation for nasal administration may be configured such that the Cmax of the steroid hormone component can be adjusted to be 15ng/ml or less. The powder preparation for nasal administration enables the concentration of a steroid hormone such as testosterone in the blood to be constrained to a specific range over a long period of time.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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