1. The compound of formula (I): or a tautomer thereof, a prodrug, or a pharmaceutically acceptable salt or solvate, wherein: Y is hydrogen or C-C1-6alkyl, and Z is selected from hydrogen, halogen, C-C1-6alkyl, C-haloalkyl, C- Alkoxy, C-haloalkoxy and -NRR； or alternatively, Y and Z are linked by a double bond (“Z = Y”), and each of them independently represents CR, CR or a nitrogen atom (N), where each of R and R is independently selected from hydrogen, halogen, hydroxyl, C-C1-6alkyl, C-Cycloalkyl, C-Haloalkyl, C-Salkoxy and C-Haloalkoxy； each of X, X, Xi is independently selected from hydrogen, halogen, hydroxyl, C-C1-6alkyl, C-Haloalkyl, C-Salkoxy and C-Haloalkoxy； R is selected from C-C1-6alkyl, C-Cycloalkyl, C-Saryl and 5-10 membered heteroaryl, 5-10 membered heterocyclyl, C-Cycloalkyl- (C-C) alkyl, C-Saryl- (C-C) alkyl, 5 -10-tsp heteroaryl- (C-C) alkyl and 5-10 membered heterocyclyl- (C-C) alkyl, each of which is optionally substituted with one, two or three substituents independently selected from halogen, hydroxyl, C-C1-6 alkyl, C-Haloalkyl , C-Salkoxy, C-Haloalkoxy, -NRR, cyano, nitro, oxo, -C (O) R, -C (O) OR and -C (O) NRR, R is hydrogen or C-C1-6alkyl, or alternatively, R and R, together with the nitrogen (N) and sulfur (S) atoms to which they are attached form a five- or six-membered ring, R represents hydrogen, C-C1-6alkyl, C-Saryl, benzyl, -C (O) R, or - C (O) OR, each of which is not optionally substituted with one, two or three substituents independently selected from halogen, C-C1-6alkyl, halogenated, C-Salkoxy, C-Salkoxy, cyano and -NRR, each of R, R, R and R independently represents hydrogen, halogen, C-Salkyl, C-haloalkyl, C-Salkoxy and C-Haloalkoxy； each of R and R is independently selected from hydrogen, C-C1-6alkyl, benzyl and —C (O) OR, and R is hydrogen or1. Соединение формулы (I):или его таутомер, пролекарство, или фармацевтически приемлемая соль или сольват, где:Y представляет собой водород или С-Салкил, и Z выбран из водорода, галогена,
