CHEN JIA SHIONG,첸, 지아-시옹,CHAO YE SU,차오, 예-수,CHEN CHIA NAN,첸, 치아-난
申请号：
KR1020190000807
公开号：
KR1020190083990A
申请日:
2019.01.03
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention relates to a method for removing immune suppression in a tumor microenvironment or stimulating an immune system against cancer cells, comprising administering a combination of a HDAC inhibitor and an NSAID in combination with an immune checkpoint inhibitor to a patient. Combination of a pharmaceutical combination and the immune checkpoint inhibitor of the present invention significantly eradicate tumors and increase a survival rate by about 70 to 80%.본 발명은 면역 체크 포인트 억제제와 조합된 HDAC 억제제 및 NSAID의 조합물을 환자에게 투여하는 것을 포함하여, 종양 미세환경에서 면역 억제를 제거하거나 암세포에 대한 면역계를 자극하는 방법에 관한 것이다.
