Implementations of a pharmaceutical composition used to help treat pain, reduce inflammation and fatigue, provide vital nutrients, and increase alertness in humans are provided. In some implementations, the pharmaceutical composition can be comprised of an effective amount of a non-steroidal anti-inflammatory drug (NSAID), a multivitamin supplement, and an effective amount of caffeine sufficient to increase alertness, metabolic activity, and/or stave off drowsiness. The pharmaceutical composition can be formulated with any suitable nontoxic pharmaceutically acceptable inert carry material known to those skilled in the art and administered orally.