A negative pressure wound therapy (NPWT) system creates and maintains a sub atmospheric pressure within a sealed wound environment for the purpose of healing wounds. The NPWT system includes a wound interface material (118) a housing (102) an osmotic membrane (116) and an evacuation port (120). The wound interface material (118) contacts a wound region and absorbs exudate from the wound region. The housing (102) defines a cavity (108) in an interior space of the housing (102). The osmotic membrane (116) is coupled to the wound interface material (118) to transfer a fluid of the exudate from the wound interface material (118) to the cavity (108) of the housing (102). The evacuation port (120) is also coupled to the wound interface material (118) to facilitate passage of a gas out of the wound interface material (118) to create a negative pressure at the wound region.