Waste clean-up and disposal devices are disclosed for scooping-up, bagging, and disposing of pet waste in a sanitary manner. The device includes a scooper body for removably housing and protecting a flexible tubing dispensing cassette. The scooper body defines a passageway between a waste entrance opening and a waste exit opening. The cassette dispenses flexible tubing from the waste exit opening for receiving waste materials such as pet waste droppings. A blade is preferably connected to the housing for severing of the flexible tubing for disposal.